NEW
YORK (Reuters Health) - Findings from an animal study suggest that disease-cause
prions can be spread via infected skeletal muscle from deer with chronic
wasting disease (CWD) -- a wildlife illness related to mad cow disease.
Whether
CWD can be passed to humans is still unclear, but the present findings suggest
that if this does occur, simply handling the meat of infected dear could pose a
risk, senior author Dr. Glenn C. Telling, from the University of Kentucky in
Lexington, and colleagues warn in the journal Science.
The
researchers injected muscle or brain extracts from CWD-affected mule deer into
the brains of mice.
As
expected, the brain extracts were much more efficient at causing disease in the
mice. Still, all of the muscle extracts caused progressive neurologic
dysfunction too, albeit with longer incubation times.
These
results show that muscle, "which is likely to be consumed by humans, is a
significant source of prion infectivity," the authors write. "Humans
consuming or handling meat from CWD-infected deer are therefore at risk to
prion exposure."
SOURCE:
Science January 26, 2006.